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Is Oral Tolerance Correlated with IgE Levels and Mast Cell Numbers?
Author(s) -
SILVA ANTONIO CARLOS,
SILVA MARIA F. S.,
BIANCHI CRISTINA,
RIBEIRO RICARDO C.,
NÓBREGA ALBERTO,
SANT'ANNA OSVALDO
Publication year - 2004
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1309.046
Subject(s) - immunoglobulin e , phenotype , biology , immunology , gene , genetics , antibody
A bstract : A triple genetic association between serum IgE levels, mast cell numbers, and susceptibility to oral tolerance was observed in mice genetically selected to extreme phenotypes of oral tolerance (susceptibility and resistance), suggesting a coadaptation of genes controlling these traits.