Selective Generation of Gut‐Tropic T Cells in Gut‐Associated Lymphoid Tissues: Requirement for GALT Dendritic Cells and Adjuvant | Zendy

SVENSSON MARCUS | Zendy; JOHANSSONLINDBOM BENGT | Zendy; WURBEL MARCANDRÉ | Zendy; MALISSEN BERNARD | Zendy; MÁRQUEZ GABRIEL | Zendy; AGACE WILLIAM | Zendy

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Selective Generation of Gut‐Tropic T Cells in Gut‐Associated Lymphoid Tissues: Requirement for GALT Dendritic Cells and Adjuvant

Author(s) -

SVENSSON MARCUS,

JOHANSSONLINDBOM BENGT,

WURBEL MARCANDRÉ,

MALISSEN BERNARD,

MÁRQUEZ GABRIEL,

AGACE WILLIAM

Publication year - 2004

Publication title -

annals of the new york academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.712

H-Index - 248

eISSN - 1749-6632

pISSN - 0077-8923

DOI - 10.1196/annals.1309.025

Subject(s) - gut associated lymphoid tissue , adjuvant , lymphatic system , biology , microbiology and biotechnology , immunology , follicular dendritic cells , chemistry , antigen presenting cell , immune system , t cell

A bstract : To gain entry into peripheral tissues, effector T lymphocytes express specific combinations of adhesion molecules and chemokine receptors. Expression of these are induced during activation in regional secondary lymphoid organs. Herein, we describe a role for GALT DCs in the generation of CCR9 + α 4 β 7 + gut tropic lymphocytes.

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