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Redox Metals in Alzheimer's Disease
Author(s) -
TODORICH BOZHO M.,
CONNOR JAMES R.
Publication year - 2004
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1306.014
Subject(s) - disease , pathogenesis , redox , copper metabolism , homeostasis , zinc , neuroscience , alzheimer's disease , multiple sclerosis , chemistry , medicine , copper , biology , pathology , microbiology and biotechnology , immunology , inorganic chemistry , organic chemistry
A bstract : Redox metals in the brain play many important roles in maintenance of cellular function. The maintenance of their homeostasis is of paramount importance to a number of diseases such as Alzheimer's disease and multiple sclerosis. Iron, copper, and zinc are metals of special interest in the pathogenesis of these disorders. This review will focus primarily on iron.