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Functional Neuroimaging of Social Cognition in Pervasive Developmental Disorders
Author(s) -
MARTINO ADRIANA,
CASTELLANOS F XAVIER
Publication year - 2003
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1301.027
Subject(s) - ventromedial prefrontal cortex , autism , neuroimaging , psychology , cognition , functional neuroimaging , prefrontal cortex , neuroscience , amygdala , social cognition , asperger syndrome , pervasive developmental disorder , developmental psychology , cognitive psychology , developmental disorder
A bstract : An emerging literature on the neuroanatomical correlates of social cognition in pervasive developmental disorders is reviewed. Studies conducted with high‐functioning adults with autism or Asperger's syndrome highlight patterns of decreased activation in ventromedial prefrontal cortex, temporo‐parietal junction, amygdala, and periamygdaloid cortex, along with aberrantly increased activation in primary sensory cortices. Future studies should extend these important initial results to younger and more severely affected subjects.