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Naturally Long‐Lived Animal Models for the Study of Slow Aging and Longevity
Author(s) -
HOLMES DONNA J.
Publication year - 2004
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1297.088
Subject(s) - longevity , vertebrate , biology , animal model , selection (genetic algorithm) , oxidative damage , zoology , evolutionary biology , gerontology , oxidative stress , medicine , endocrinology , computer science , biochemistry , artificial intelligence , gene
A bstract : Judicious selection of new animal models for the study of basic aging processes must combine feasibility and good use of the comparative method with evidence of antiaging adaptations, like the ability to combat oxidative damage to cells and tissues. A number of vertebrate species already in use or being developed as new biomedical models lend themselves very well to laboratory studies of aging, including small birds, bats, and mole‐rats.