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A Protein‐Based Three Terminal Electronic Device
Author(s) -
RINALDI ROSS,
MARUCCIO GIUSEPPE,
BIASCO ADRIANA,
VISCONTI PAOLO,
ARIMA VALENTINA,
CINGOLANI ROBERTO
Publication year - 2003
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1196/annals.1292.012
Subject(s) - azurin , nanoelectronics , terminal (telecommunication) , copper protein , realization (probability) , electron transfer , nanotechnology , intramolecular force , bioelectronics , transistor , materials science , voltage , chemistry , optoelectronics , computer science , copper , electrical engineering , biosensor , engineering , telecommunications , statistics , mathematics , organic chemistry , stereochemistry , metallurgy
A bstract : Because of their natural functional characteristics, involving inter‐ and intramolecular electron transfer, metalloproteins are good candidates for biomolecular nanoelectronics. In particular, blue copper proteins, such as azurin, can bind gold via a disulfide site present on its surface and they have a natural electron transfer activity that can be exploited for the realization of molecular switches whose conduction state can be controlled by tuning their redox state through an external voltage source. We report on the implementation of a prototype of protein transistor operating in air and in the solid state, based on this class of proteins. The three terminal devices exhibit various functions depending on the relative source‐drain and gate‐drain voltages bias, opening a way to the implementation of a new generation of logic architectures.