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Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators
Author(s) -
Raza Sobia,
Barnett Mark W.,
BarnettItzhaki Zohar,
Amit Ido,
Hume David A.,
Freeman Tom C.
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.6hi0313-169r
Subject(s) - biology , tlr4 , transcriptional regulation , transcription factor , microbiology and biotechnology , signal transduction , proinflammatory cytokine , microarray analysis techniques , gene , major histocompatibility complex , gene regulatory network , regulation of gene expression , immunology , gene expression , genetics , computational biology , inflammation
Analysis of transcriptomics data reveals the LPS response can be subdivided into a larger number of co‐regulated gene subsets than previously considered.