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Chronic alcohol ingestion modulates hepatic macrophage populations and functions in mice
Author(s) -
Wang Meng,
You Qiang,
Lor Kenton,
Chen Fangfang,
Gao Bin,
Ju Cynthia
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.6a0114-004rr
Subject(s) - phenotype , pathogenesis , biology , proinflammatory cytokine , alcoholic liver disease , phagocytosis , inflammation , integrin alpha m , population , macrophage , microbiology and biotechnology , immunology , cancer research , immune system , gene , in vitro , medicine , genetics , cirrhosis , environmental health
Chronic alcohol ingestion leads to the recruitment of infiltrating macrophages into the liver, which show distinguished phenotypes and functions from liver‐ resident Kupffer cells.