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Myeloid‐derived suppressor cells and T regulatory cells in tumors: unraveling the dark side of the force
Author(s) -
Hatziioannou Aikaterini,
Alissafi Themis,
Verginis Panayotis
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.5vmr1116-493r
Subject(s) - biology , immune system , suppressor , myeloid derived suppressor cell , immunology , myeloid , cancer research , immunotherapy , function (biology) , acquired immune system , immune tolerance , cancer , microbiology and biotechnology , genetics
Review on how MDSCs and Tregs promote tumor development and progression, and impede cancer immunotherapy.