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CD4 + T cell STAT3 phosphorylation precedes acute GVHD, and subsequent Th17 tissue invasion correlates with GVHD severity and therapeutic response
Author(s) -
Betts Brian C.,
Sagatys Elizabeth M.,
Veerapathran Anandharaman,
Lloyd Mark C.,
Beato Francisca,
Lawrence Harshani R.,
Yue Binglin,
Kim Jongphil,
Sebti Said M.,
Anasetti Claudio,
Pidala Joseph
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.5a1114-532rr
Subject(s) - stat3 , blockade , rar related orphan receptor gamma , immunology , biology , cancer research , interleukin 17 , signal transduction , immune system , receptor , microbiology and biotechnology , foxp3 , biochemistry
CD4 + T cell STAT3 Y705 activation and subsequent Th17 tissue invasion correlates with acute GVHD after allogeneic hematopoietic cell transplantation.
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