Premium
Synovial IL‐21/TNF‐producing CD4 + T cells induce joint destruction in rheumatoid arthritis by inducing matrix metalloproteinase production by fibroblast‐like synoviocytes
Author(s) -
Lebre Maria C.,
Vieira Pedro L.,
Tang Man Wai,
Aarrass Saïda,
Helder Boy,
NewsomDavis Thomas,
Tak Paul P.,
Screaton Gavin R.
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.5a0516-217rr
Subject(s) - matrix metalloproteinase , rheumatoid arthritis , fibroblast , tumor necrosis factor alpha , matrix metalloproteinase 3 , biology , immunology , synovial membrane , cancer research , matrix (chemical analysis) , metalloproteinase , microbiology and biotechnology , in vitro , materials science , biochemistry , composite material
Synovial IL‐21 + TNF + CD4 + T cells induce matrix metalloproteinase production by fibroblast‐like synoviocytes in RA patients.