Premium
Engineering macrophages to eat cancer: from “marker of self” CD47 and phagocytosis to differentiation
Author(s) -
Alvey Cory,
Discher Dennis E.
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4ri1216-516r
Subject(s) - cd47 , phagocytosis , biology , macrophage , immune system , microbiology and biotechnology , cancer cell , cancer , immunology , cancer research , in vitro , genetics
Review on how a deeper understanding of biophysical interactions between macrophages, CD47, tumor cells, and microenvironments could re‐invigorate macrophage immunotherapies.