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Hematopoietic LTβR deficiency results in skewed T cell cytokine profiles during a mucosal viral infection
Author(s) -
Sun Tian,
Rojas Olga L.,
Li Conglei,
Philpott Dana J.,
Gommerman Jennifer L.
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4mab0715-294r
Subject(s) - lymphotoxin , lymphotoxin beta receptor , biology , immunology , lymphotoxin alpha , lamina propria , cytokine , cytokine receptor , immune system , microbiology and biotechnology , epithelium , genetics
Deletion of LTβR in the myeloid compartment results in an altered cellular immune response to mucosal viral infection, without a defect in viral clearance.