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NK cells inhibit humoral immunity by reducing the abundance of CD4 + T follicular helper cells during a chronic virus infection
Author(s) -
Cook Kevin D.,
Kline Hannah C.,
Whitmire Jason K.
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4hi1214-594r
Subject(s) - biology , antibody , immunology , virus , immunity , cd8 , chronic infection , immune system , cell , t cell , interleukin 21 , virology , genetics
Virus persistence is increased by NK cells that inhibit antiviral CD4 + TFH cells and early B cell responses.