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Functional analysis of NK cell subsets activated by 721.221 and K562 HLA‐null cells
Author(s) -
Lisovsky Irene,
Isitman Gamze,
Bruneau Julie,
Bernard Nicole F.
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4ab1014-499r
Subject(s) - k562 cells , biology , interleukin 21 , lymphokine activated killer cell , immunology , interleukin 12 , microbiology and biotechnology , cell , immune system , t cell , in vitro , cytotoxic t cell , leukemia , genetics
Higher frequency 721 stimulated NK cells secrete IFN‐ γ and/or CCL4, while CD107a expression dominates the response to K562.