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LL‐37 modulates human neutrophil responses to influenza A virus
Author(s) -
Tripathi Shweta,
Verma Anamika,
Kim EunJeong,
White Mitchell R.,
Hartshorn Kevan L.
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4a1113-604rr
Subject(s) - influenza a virus , biology , proinflammatory cytokine , in vivo , formyl peptide receptor , immunology , nadph oxidase , innate immune system , cathelicidin , ex vivo , neutrophil extracellular traps , receptor , in vitro , inflammation , virus , microbiology and biotechnology , immune system , reactive oxygen species , chemotaxis , biochemistry
LL‐37 upregulates neutrophil respiratory burst and extracellular trap formation in response to influenza A virus, but reduces cytokine generation triggered by the virus.