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Antibody blockade of IL‐17 family cytokines in immunity to acute murine oral mucosal candidiasis
Author(s) -
Whibley Natasha,
Tritto Elaine,
Traggiai Elisabetta,
Kolbinger Frank,
Moulin Pierre,
Brees Dominique,
Coleman Bianca M.,
Mamo Anna J.,
Garg Abhishek V.,
Jaycox Jillian R.,
Siebenlist Ulrich,
Kammüller Michael,
Gaffen Sarah L.
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4a0915-428r
Subject(s) - immunology , biology , interleukin 17 , antibody , candida albicans , blocking antibody , cytokine , blockade , immunity , interleukin 23 , receptor , immune system , microbiology and biotechnology , biochemistry
OPC requires IL‐17R signaling in mice and humans; IL‐17A, but not IL‐17F blockade, predisposes to OPC, and functional redundancy among cytokines is evident.