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Simian immunodeficiency virus infection and immune responses in the pig‐tailed macaque testis
Author(s) -
Winnall Wendy R.,
Lloyd Sarah B.,
De Rose Robert,
Alcantara Sheilajen,
Amarasena Thakshila H.,
Hedger Mark P.,
Girling Jane E.,
Kent Stephen J.
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4a0914-438r
Subject(s) - biology , simian immunodeficiency virus , immunology , cd8 , immunosuppression , immune system , t cell , virology , macaque , paleontology
Simian immunodeficiency virus infection of the macaque testis leads to loss of intratesticular CD4 + cells and an influx of CD8 + cells with diminished cytokine responsiveness.