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Autophagy suppresses host adaptive immune responses toward Borrelia burgdorferi
Author(s) -
Buffen Kathrin,
Oosting Marije,
Li Yang,
Kanneganti ThirumalaDevi,
Netea Mihai G.,
Joosten Leo A. B.
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4a0715-331r
Subject(s) - borrelia burgdorferi , autophagy , biology , immune system , acquired immune system , interleukin , cytokine , borrelia , innate immune system , spirochaetaceae , immunology , microbiology and biotechnology , antibody , apoptosis , biochemistry
Inhibition of autophagy increases the severity of murine Lyme arthritis and human adaptive immune responses against B. burgdorferi .