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Unmethylated CpG motifs in the L. donovani DNA regulate TLR9‐dependent delay of programmed cell death in macrophages
Author(s) -
Das Sushmita,
Ghosh Ayan Kumar,
Singh Shikha,
Saha Bhaskar,
Ganguly Ashish,
Das Pradeep
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4a0713-378rr
Subject(s) - biology , tlr9 , cpg site , programmed cell death , dna , cpg oligodeoxynucleotide , microbiology and biotechnology , virology , apoptosis , genetics , gene , dna methylation , gene expression
Species‐specific unmethylated CpG‐motifs in L. donovani DNA in modulating macrophage apoptosis through TLR9 and activation of the PI3K/Akt pathway.