Neutrophil extracellular traps release induced by  Leishmania : role of PI3Kγ, ERK, PI3Kσ, PKC, and [Ca 2+ ] | Zendy

DeSouzaVieira Thiago | Zendy; GuimarãesCosta Anderson | Zendy; Rochael Natalia C. | Zendy; Lira Maria N. | Zendy; Nascimento Michelle T. | Zendy; LimaGomez Phillipe de Souza | Zendy; Mariante Rafael M. | Zendy; Persechini Pedro M. | Zendy; Saraiva Elvira M. | Zendy

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Neutrophil extracellular traps release induced by Leishmania : role of PI3Kγ, ERK, PI3Kσ, PKC, and [Ca 2+ ]

Author(s) -

DeSouzaVieira Thiago,

GuimarãesCosta Anderson,

Rochael Natalia C.,

Lira Maria N.,

Nascimento Michelle T.,

LimaGomez Phillipe de Souza,

Mariante Rafael M.,

Persechini Pedro M.,

Saraiva Elvira M.

Publication year - 2016

Publication title -

journal of leukocyte biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.819

H-Index - 191

eISSN - 1938-3673

pISSN - 0741-5400

DOI - 10.1189/jlb.4a0615-261rr

Subject(s) - neutrophil extracellular traps , microbiology and biotechnology , biology , extracellular , leishmania , pi3k/akt/mtor pathway , intracellular , reactive oxygen species , mapk/erk pathway , programmed cell death , signal transduction , kinase , immunology , inflammation , biochemistry , parasite hosting , apoptosis , world wide web , computer science

PI3Kγ‐mediated activation of ERK regulates oxidative burst‐dependent netosis, while PI3Kσ and calcium are key signals for netosis independent of oxidative burst induced by Leishmania .

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