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PGE 2 ‐treated macrophages inhibit development of allergic lung inflammation in mice
Author(s) -
Draijer Christina,
Boorsma Carian E.,
RekerSmit Catharina,
Post Eduard,
Poelstra Klaas,
Melgert Barbro N.
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3mab1115-505r
Subject(s) - inflammation , immunology , house dust mite , macrophage polarization , macrophage , lung , adoptive cell transfer , biology , allergic inflammation , m2 macrophage , immune system , medicine , allergy , in vitro , allergen , t cell , biochemistry
Redirecting macrophage polarization with PGE 2 inhibits development of allergic lung inflammation, and independent of macrophage origin, increasing its potential for therapy.