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Frontline Science: HIV infection of Kupffer cells results in an amplified proinflammatory response to LPS
Author(s) -
Mosoian Arevik,
Zhang Lumin,
Hong Feng,
Cunyat Francesc,
Rahman Adeeb,
Bhalla Riti,
Panchal Ankur,
Saiman Yedidya,
Fiel M. Isabel,
Florman Sander,
Roayaie Sasan,
Schwartz Myron,
Branch Andrea,
Stevenson Mario,
Bansal Meena B.
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3hi0516-242r
Subject(s) - tlr4 , proinflammatory cytokine , biology , cd14 , immunology , inflammation , immune system , kupffer cell , innate immune system , macrophage , tumor necrosis factor alpha , in vitro , biochemistry
HIV‐1 infection of KCs leads to dysregulated innate immune response to LPS, and may play a role in hepatic inflammation and fibrosis.