Premium
TLR10 suppresses the activation and differentiation of monocytes with effects on DC‐mediated adaptive immune responses
Author(s) -
Hess Nicholas J.,
Felicelli Christopher,
Grage Jennifer,
Tapping Richard I.
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a1116-492r
Subject(s) - biology , proinflammatory cytokine , microbiology and biotechnology , innate immune system , immunology , immune system , cytokine , cd40 , acquired immune system , pattern recognition receptor , inflammation , cytotoxic t cell , biochemistry , in vitro
Engagement of TLR10 on primary human monocytes has both immediate and long‐term suppressive effects on the inflammatory response.