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Estrogen anti‐inflammatory activity on human monocytes is mediated through cross‐talk between estrogen receptor ERα36 and GPR30/GPER1
Author(s) -
Pelekanou Vasiliki,
Kampa Marilena,
Kiagiadaki Foteini,
Deli Alexandra,
Theodoropoulos Panayiotis,
Agrogiannis George,
Patsouris Efstratios,
Tsapis Andreas,
Castanas Elias,
Notas George
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0914-430rr
Subject(s) - estrogen receptor , gper , estrogen receptor beta , estrogen , biology , estrogen receptor alpha , receptor , estrogen related receptor gamma , monocyte , cancer research , microbiology and biotechnology , endocrinology , medicine , biochemistry , immunology , cancer , breast cancer , genetics
Ligand‐activated ER, ERα36, inhibits LPS‐induced IL‐6 expression in human monocytes via inhibition of NFκB transcriptional activity, in a GPR30/GPER1‐dependent manner.