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Fluid shear‐induced cathepsin B release in the control of Mac1‐dependent neutrophil adhesion
Author(s) -
Akenhead Michael L.,
Fukuda Shunichi,
SchmidSchoünbein Geert W.,
Shin Hainsworth Y.
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0716-317rr
Subject(s) - microcirculation , biology , cd18 , microbiology and biotechnology , cell adhesion , inflammation , endothelium , focal adhesion , immunology , cell , signal transduction , medicine , flow cytometry , endocrinology , integrin alpha m , biochemistry
Cathepsin B is part of a shear stress mechanotransduction control mechanism, which restricts leukocyte adhesion in the physiological microcirculation.