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Enhanced suppression of polyclonal CD8 + 25 + regulatory T cells via exosomal arming of antigen‐specific peptide/MHC complexes
Author(s) -
Mu Chuanyong,
Zhang Xueshu,
Wang Lu,
Xu Aizhang,
Ahmed Khawaja Ashfaque,
Pang Xueqin,
Chibbar Rajni,
Freywald Andrew,
Huang Jianan,
Zhu Yehan,
Xiang Jim
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0716-295rr
Subject(s) - cytotoxic t cell , ctl* , biology , priming (agriculture) , cd8 , immunology , cd80 , t cell , cd86 , microbiology and biotechnology , immune system , in vitro , cd40 , biochemistry , botany , germination
Antigen specificity to enhance immune suppression by nonspecific polyclonal CD8 + 25 + Tr‐cells can be achieved through exosomal pMHC arming.