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Sensitivity of dendritic cells to NK‐mediated lysis depends on the inflammatory environment and is modulated by CD54/CD226‐driven interactions
Author(s) -
Smith Laura E.,
Olszewski Marcin A.,
Georgoudaki AnnaMaria,
Wagner Arnika K.,
Hägglöf Thomas,
Karlsson Mikael C. I.,
DominguezVillar Margarita,
GarciaCozar Francisco,
Mueller Steffan,
Ravens Inga,
Bernhardt Günter,
Chambers Benedict J.
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0615-271rr
Subject(s) - dendritic cell , interleukin 12 , microbiology and biotechnology , biology , follicular dendritic cells , antigen presenting cell , myeloid derived suppressor cell , immune system , lymphokine activated killer cell , interleukin 21 , janus kinase 3 , cytotoxic t cell , immunology , t cell , in vitro , biochemistry , suppressor , gene
GM‐CSF stimulation of Flt3L‐derived DCs increases their sensitivity to NK cells by up‐regulation of receptors recognized by NK cells.