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Milk fat globule epidermal growth factor‐8 limits tissue damage through inflammasome modulation during renal injury
Author(s) -
Brissette MarieJoëlle,
Laplante Patrick,
Qi Shijie,
Latour Mathieu,
Cailhier JeanFrancois
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0515-213rr
Subject(s) - inflammasome , proinflammatory cytokine , biology , kidney , epidermal growth factor , inflammation , macrophage , cancer research , cytokine , growth factor , immunology , endocrinology , receptor , biochemistry , in vitro
MFG‐E8‐reprogramming of macrophages has a protective role in UUO through inflammasome modulation, preventing severe tissue damage and fibrosis.