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Mediators and molecular pathways involved in the regulation of neutrophil extracellular trap formation mediated by activated platelets
Author(s) -
Carestia Agostina,
Kaufman Tomás,
Rivadeneyra Leonardo,
Landoni Verónica Inés,
Pozner Roberto Gabriel,
Negrotto Soledad,
D’Atri Lina Paola,
Gómez Ricardo Martín,
Schattner Mirta
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0415-161r
Subject(s) - neutrophil extracellular traps , extracellular , platelet , platelet activation , microbiology and biotechnology , biology , biochemistry , immunology , inflammation
Platelet GPIb and neutrophil CD18 together with TXA 2 , PF4, and vWF release mediate platelet‐triggered NET formation, while prostacyclin inhibits NETosis.