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Enhancement of humoral immunity by the type II heat‐labile enterotoxin LT‐IIb is dependent upon IL‐6 and neutrophils
Author(s) -
Greene Christopher J.,
Hu John C.,
Vance David J.,
Rong Yinghui,
Mandell Lorrie,
KingLyons Natalie,
MassoWelch Patricia,
Mantis Nicholas J.,
Connell Terry D.
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0415-153rr
Subject(s) - adjuvant , immune system , heat labile enterotoxin , biology , antigen , enterotoxin , immunology , immunization , intradermal injection , interleukin , microbiology and biotechnology , cytokine , escherichia coli , biochemistry , gene
Augmented and accelerated production of Ag‐specific Abs by the i.d. adjuvant LT‐IIb requires recruitment of neutrophils and expression of IL‐6.