Premium
Dexamethasone rapidly suppresses IL‐33‐stimulated mast cell function by blocking transcription factor activity
Author(s) -
Paranjape Anuya,
Chernushevich Oksana,
Qayum Amina Abdul,
Spence Andrew J.,
Taruselli Marcela T.,
Abebayehu Daniel,
Barnstein Brian O.,
McLeod Jamie Josephine Avila,
Baker Bianca,
Bajaj Gurjas S.,
Chumanevich Alena P.,
Oskeritzian Carole A.,
Ryan John J.
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0316-125r
Subject(s) - interleukin 33 , mast cell , dexamethasone , cytokine , proinflammatory cytokine , biology , immunoglobulin e , immunology , inflammation , endocrinology , medicine , interleukin , antibody
Dex suppresses IL‐33‐stimulated mast cell functions in vitro and in vivo, where the predominant mechanism appears to be a blockade of transcriptional activity.