Premium
Phosphodiesterase 2A is a major negative regulator of iNOS expression in lipopolysaccharide‐treated mouse alveolar macrophages
Author(s) -
Rentsendorj Otgonchimeg,
D'Alessio Franco R.,
Pearse David B.
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0314-152r
Subject(s) - lipopolysaccharide , gene knockdown , macrophage , biology , microbiology and biotechnology , alveolar macrophage , cell culture , immunology , biochemistry , in vitro , genetics
Mouse alveolar macrophage PDE2A significantly inhibits the increased iNOS expression resulting from LPS exposure.