Premium
CD40 promotes MHC class II expression on adipose tissue macrophages and regulates adipose tissue CD4 + T cells with obesity
Author(s) -
Morris David L.,
Oatmen Kelsie E.,
Mergian Taleen A.,
Cho Kae Won,
DelProposto Jennifer L.,
Singer Kanakadurga,
EvansMolina Carmella,
O’Rourke Robert W.,
Lumeng Carey N.
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.3a0115-009r
Subject(s) - adipose tissue , cd40 , biology , adipose tissue macrophages , cd86 , endocrinology , medicine , inflammation , cd80 , immune system , white adipose tissue , immunology , t cell , cytotoxic t cell , biochemistry , in vitro
CD40‐deficient mice fail to induce conventional CD4 + cells in adipose tissue associated with decreased markers of antigen presentation in ATMs.