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TRIF‐dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target
Author(s) -
Ullah M. Obayed,
Sweet Matthew J.,
Mansell Ashley,
Kellie Stuart,
Kobe Bostjan
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2ri1115-531r
Subject(s) - trif , biology , inflammation , host (biology) , microbiology and biotechnology , signal transduction , immunology , innate immune system , immune system , toll like receptor , ecology
Review of the TRIF adaptor protein's role in TLR signaling pathways, and its involvement in disease processes.