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Effective T helper cell responses against retroviruses: are all clonotypes equal?
Author(s) -
Thorborn Georgina,
Young George R.,
Kassiotis George
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2ri0613-347r
Subject(s) - biology , cytotoxic t cell , immunology , t cell , immune system , epitope , cd8 , t cell receptor , effector , acquired immune system , virology , antigen , genetics , in vitro
Review on distinct CD4 + T cell clonotypes, with varying protective capacities against retroviruses, reveals targets for manipulation during natural infection or vaccination.