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Lipid raft‐mediated Fas/CD95 apoptotic signaling in leukemic cells and normal leukocytes and therapeutic implications
Author(s) -
Gajate Consuelo,
Mollinedo Faustino
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2mr0215-055r
Subject(s) - biology , fas receptor , apoptosis , lipid raft , microbiology and biotechnology , raft , cancer research , immunology , signal transduction , programmed cell death , genetics , chemistry , organic chemistry , copolymer , polymer
Review of how lipid rafts affect Fas/CD95 apoptotic signaling in hematologic cancer and normal cells, and their therapeutic prospects in cancer and autoimmune diseases.