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The granulocyte orphan receptor CEACAM4 is able to trigger phagocytosis of bacteria
Author(s) -
Delgado Tasco´n Julia,
Adrian Jonas,
Kopp Kathrin,
Scholz Philipp,
Tschan Mario P.,
Kuespert Katharina,
Hauck Christof R.
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2ab0813-449rr
Subject(s) - biology , internalization , phagocytosis , orphan receptor , receptor , bacteria , microbiology and biotechnology , proto oncogene tyrosine protein kinase src , transmembrane protein , biochemistry , genetics , gene , transcription factor
CEACAM4 contains a functional immunoreceptor tyrosinebased activation motif, which is tyrosine‐phosphorylated, and initiates efficient phagocytosis of attached bacteria.

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