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The Cebpa +37‐kb enhancer directs transgene expression to myeloid progenitors and to long‐term hematopoietic stem cells
Author(s) -
Guo Hong,
Ma Ou,
Friedman Alan D.
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2ab0314-145r
Subject(s) - cebpa , biology , myeloid , haematopoiesis , enhancer , cancer research , myelopoiesis , transgene , microbiology and biotechnology , progenitor cell , stem cell , gene expression , transcription factor , genetics , gene
The Cebpa +37‐kb enhancer directs preferential expression to myeloid, as compared to megakaryocyte/erythroid or lymphoid progenitors, and to functional long‐term hematopoietic stem cells.