Premium
The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4
Author(s) -
Verstak Brett,
Stack Julianne,
Ve Thomas,
Mangan Matthew,
Hjerrild Kathryn,
Jeon Jannah,
Stahl Rainer,
Latz Eicke,
Gay Nick,
Kobe Bostjan,
Bowie Andrew G.,
Mansell Ashley
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2a0913-487r
Subject(s) - trif , signal transducing adaptor protein , biology , microbiology and biotechnology , tlr4 , innate immune system , signal transduction , ectopic expression , immune system , hek 293 cells , toll like receptor , immunology , receptor , cell culture , biochemistry , genetics
TRAM interaction with TRAF6 regulates the inflammatory response to TLR4 activation, and adds further intricacy to TLR signaling.