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Human plasmacytoid dendritic cells regulate IFN‐α production through activation‐induced splicing of IL‐18Rα
Author(s) -
Chao Yinxia,
Kaliaperumal Nivashini,
Chretien AnneSophie,
Tang Suisheng,
Lee Bernett,
Poidinger Michael,
Fairhurst AnnaMarie,
Connolly John E.
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2a0813-465rr
Subject(s) - biology , decoy , rna splicing , microbiology and biotechnology , receptor , function (biology) , signal transduction , gene , rna , biochemistry
A novel IL‐18Rα isoform and activation‐induced splicing of IL‐18Rα down‐modulates IFNα production in human pDCs upon viral exposure.