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A negative‐feedback function of PKC β in the formation and accumulation of signaling‐active B cell receptor microclusters within B cell immunological synapse
Author(s) -
Liu Ce,
Zhao XingWang,
Xu LiLing,
Yi JunYang,
Shaheen Samina,
Han Weidong,
Wang Fei,
Zheng Wenjie,
Xu Chenqi,
Liu Wanli
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2a0714-320r
Subject(s) - immunological synapse , protein kinase c , microbiology and biotechnology , breakpoint cluster region , signal transduction , biology , cell , receptor , t cell , biochemistry , immunology , t cell receptor , immune system
PKC β plays negative feedback function through the phosphorylation of Btk at S180 in the formation and accumulation of BCR microclusters within B cell IS.
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