Premium
TLR ligands up‐regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF‐κB‐dependent signaling pathways
Author(s) -
Xu Jun,
Zoltick Philip W.,
Gamero Ana M.,
Gallucci Stefania
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2a0713-393rr
Subject(s) - biology , microbiology and biotechnology , signal transduction , nf κb , interferon , nfkb1 , immunology , transcription factor , biochemistry , gene
The regulation of Trex1 expression by TLRs, type I IFNs, and virus, implicates a novel role for Trex1 in DC immune activation.