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MAP kinase p38 α regulates type III interferon ( IFN‐ λ 1 ) gene expression in human monocyte‐derived dendritic cells in response to RNA stimulation
Author(s) -
Jiang Miao,
O¨sterlund Pamela,
Fagerlund Riku,
Rios Dia.,
Hoffmann Alexander,
Poranen Minna M.,
Bamford Dennis H.,
Julkunen Ilkka
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2a0114-059rr
Subject(s) - irf3 , biology , irf7 , microbiology and biotechnology , interferon , gene expression , mapk/erk pathway , regulation of gene expression , signal transduction , p38 mitogen activated protein kinases , gene , transcription factor , virology , genetics
p38 α MAPK positively regulates the expression of early IFNgenes after RNA stimulation via a pathway in co‐operation withIRF3 and NF‐ κ B.
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