Premium
Nck adaptor proteins modulate differentiation and effector function of T cells
Author(s) -
Lu KunHui,
Keppler Selina,
Leithäuser Frank,
Mattfeldt Torsten,
Castello Angelo,
Kostezka Ulrike,
Küblbeck Günter,
Schmitt Sabine,
Klevenz Alexandra,
Prokosch Sandra,
Pougialis Georg,
Pawson Tony,
Batista Facundo,
Tafuri Anna,
Arnold Bernd
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1hi1114-565r
Subject(s) - biology , effector , microbiology and biotechnology , t cell , t cell receptor , signal transducing adaptor protein , immune system , signal transduction , immunology
Loss of Nck proteins in T cells impairs germinal center formation, Tfh cell survival, cytokine production, and T cell‐dependent antibody responses.