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Disruption of Trim9 function abrogates macrophage motility in vivo
Author(s) -
Tokarz Debra A.,
Heffelfinger Amy K.,
Jima Dereje D.,
Gerlach Jamie,
Shah Radhika N.,
RodriguezNunez Ivan,
Kortum Amanda N.,
Fletcher Ashley A.,
Nordone Shila K.,
Law J. McHugh,
Heber Steffen,
Yoder Jeffrey A.
Publication year - 2017
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1a0816-371r
Subject(s) - biology , zebrafish , immune system , microbiology and biotechnology , ubiquitin ligase , transcriptome , innate immune system , motility , acquired immune system , in vivo , gene expression profiling , gene expression , immunology , ubiquitin , gene , genetics
Expression of dominant‐negative Trim9 in zebrafish macrophages alters their cell shape and significantly reduces their motility in vivo.