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Soluble β‐glucan from Grifola frondosa induces tumor regression in synergy with TLR9 agonist via dendritic cell‐mediated immunity
Author(s) -
Masuda Yuki,
Nawa Daiki,
Nakayama Yoshiaki,
Konishi Morichika,
Nanba Hiroaki
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1a0814-415rr
Subject(s) - dendritic cell , biology , cytotoxic t cell , t cell , priming (agriculture) , interleukin 12 , cd40 , immunology , immune system , microbiology and biotechnology , biochemistry , in vitro , botany , germination
Cancer therapy using a TLR9 agonist and β‐glucan from Grifola frondosa synergistically induced dendritic cell maturation, inducing a Th1‐type response and tumor regression.