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TNF‐α‐mediated microRNA‐136 induces differentiation of myeloid cells by targeting NFIA
Author(s) -
Mei Shiyue,
Liu Yu,
Wu Xue,
He Qingsheng,
Min Siping,
Li Ling,
Zhang Yuan,
Yang Rongcun
Publication year - 2016
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1a0115-032rr
Subject(s) - biology , microrna , microbiology and biotechnology , ectopic expression , immune system , u937 cell , cd14 , cellular differentiation , transcription factor , integrin alpha m , myeloid , tumor necrosis factor alpha , cancer research , immunology , cell culture , gene , genetics
miRNA‐136 up‐regulation by TNF‐α and the resulting degradation of NFIA is a mechanism that controls myeloid cell differentiation.