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Oral administration of carbonic anhydrase I ameliorates murine experimental colitis induced by Foxp3 − CD4 + CD25 − T cells
Author(s) -
Mori Kenichirou,
Yamanishi Hirofumi,
Ikeda Yoshiou,
Kumagi Teru,
Hiasa Yoichi,
Matsuura Bunzo,
Abe Masanori,
Onji Morikazu
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1212612
Subject(s) - foxp3 , il 2 receptor , colitis , immunology , antigen , biology , cd11c , adoptive cell transfer , oral administration , immune system , rar related orphan receptor gamma , t cell , pharmacology , biochemistry , gene , phenotype
Oral tolerization with carbonic anhydrase I induces antigen‐specific protection from murine experimental colitis, by inducing CD103+ dendritic cells and generating Foxp3+CD4+CD25+ regulatory T cells.