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BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction
Author(s) -
Shubin Nicholas J.,
Chung Chun S.,
Heffernan Daithi S.,
Irwin Lydea R.,
Monaghan Sean F.,
Ayala Alfred
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1211641
Subject(s) - btla , immunology , innate immune system , biology , immune system , sepsis , inflammation , monocyte , t cell
BTLA expression contributes to increased septic morbidity, mortality, and decreased innate cell activity in mice, while BTLA + blood monocyte levels increase in septic ICU patients.
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